Is Non-Nutritive Sucking An Effective Method Of Providing Analgesia To Newborns Undergoing Painful Procedures?

OBJECTIVE: “The objective of this selective EBM review is to determine whether or not nonnutritive sucking is an effective method of providing analgesia to infants undergoing painful procedures.” STUDY DESIGN: A systematic review of three blinded randomized-controlled trials (RCT’s), published from 2011 to 2013. All were published in English, one of which was translated from its original Spanish version to an English publication. DATA SOURCES: Three RCT’s were found using the PubMed database and all were published in peer-reviewed journals. OUTCOMES MEASURED: The incidence and severity of pain were measured during procedures using the Premature Infant Pain Profile (PIPP) and/or Neonatal Infant Pain Scores (NIPS). RESULTS: The first study, Lima et al reported that during venipuncture, both nutritive and nonnutritive sucking provided lower pain response compared to the control group receiving no analgesic stimulus (P0.05) suggesting adequate analgesic relief in the control group. Lastly, Liaw et al, demonstrated that non-nutritive sucking during heel-stick procedures had the lowest mean PIPP scores (6.39) as compared to facilitated tucking (7.15) and the control (9.52), which received only routine care. Additionally, odds ratios for pain and severe pain in the NNS vs. control groups were 0.39 and 0.23 respectively, indicating the NNS group had a reduced change of experiencing pain. CONCLUSIONS: All three RCT’s reported reduced incidence and severity of pain in these infants, thus suggesting that non-nutritive sucking does provide adequate analgesia during procedures that typically induce painful stimulation

Payload/orbiter contamination control requirement study: Computer interface

The MSFC computer facilities, and future plans for them are described relative to characteristics of the various computers as to availability and suitability for processing the contamination program. A listing of the CDC 6000 series and UNIVAC 1108 characteristics is presented so that programming requirements can be compared directly and differences noted

Payload/orbiter contamination control requirement study: Preliminary contamination mission support plan

Progress is reported on the mission support plan and those support activities envisioned to be applicable and necessary during premission and postmission phases of the Spacelab program. The purpose, role, and requirements of the contamination control operations for the first two missions of the Spacelab equipped Space Transportation System are discussed. The organization of the contamination control operation and its relationship to and interfaces with other mission support functions is also discussed. Some specific areas of contamination to be investigated are treated. They are: (1) windows and viewports, (2) experiment equipment, (3) thermal control surfaces, (4) the contaminant induced atmosphere (as differentiated from the normal ambient atmosphere at the orbit altitude), and (5) optical navigation instruments

An Analysis of the Relationship between Study Styles and Demographics across Multiple Accounting Class Levels

Approaches to learning are elemental to a student’s learning outcomes. Prior research indicates that accounting students with a deep learning approach have a more successful student learning outcome than do accounting students with a surface learning approach. Accounting accreditation and regulatory agencies have recommended that coursework be directed towards more critical thinking and real-life preparation of students. These characteristics are indicative of the deep learning approach. After ascertaining the learning approach adopted by introductory, intermediate, and advance accounting students at a public university with a main and satellite campus, this paper reports on demographic characteristics that may impact a student’s selection of learning approaches

A survey of orthopaedic journal editors determining the criteria of manuscript selection for publication

Background: To investigate the characteristics of editors and criteria used by orthopaedic journal editors in assessing submitted manuscripts. Methods: Between 2008 to 2009 all 70 editors of Medline listed orthopaedic journals were approached prospectively with a questionnaire to determine the criteria used in assessing manuscripts for publication. Results: There was a 42% response rate. There was 1 female editor and the rest were male with 57% greater than 60 years of age. 67% of the editors worked in university teaching hospitals and 90% of publications were in English.The review process differed between journals with 59% using a review proforma, 52% reviewing an anonymised manuscript, 76% using a routine statistical review and 59% of journals used 2 reviewers routinely. In 89% of the editors surveyed, the editor was able to overrule the final decision of the reviewers.Important design factors considered for manuscript acceptance were that the study conclusions were justified (80%), that the statistical analysis was appropriate (76%), that the findings could change practice (72%). The level of evidence (70%) and type of study (62%) were deemed less important. When asked what factors were important in the manuscript influencing acceptance, 73% cited an understandable manuscript, 53% cited a well written manuscript and 50% a thorough literature review as very important factors. Conclusions: The editorial and review process in orthopaedic journals uses different approaches. There may be a risk of language bias among editors of orthopaedic journals with under-representation of non-English publications in the orthopaedic literature

Temperature sensitivity of the pyloric neuromuscular system and its modulation by dopamine

We report here the effects of temperature on the p1 neuromuscular system of the stomatogastric system of the lobster (Panulirus interruptus). Muscle force generation, in response to both the spontaneously rhythmic in vitro pyloric network neural activity and direct, controlled motor nerve stimulation, dramatically decreased as temperature increased, sufficiently that stomach movements would very unlikely be maintained at warm temperatures. However, animals fed in warm tanks showed statistically identical food digestion to those in cold tanks. Applying dopamine, a circulating hormone in crustacea, increased muscle force production at all temperatures and abolished neuromuscular system temperature dependence. Modulation may thus exist not only to increase the diversity of produced behaviors, but also to maintain individual behaviors when environmental conditions (such as temperature) vary